“The ASBMB has profoundly influenced discovery, and the importance of BMB in our current era is growing, not shrinking. This is obvious just by looking at the approximately one-third of human open reading frames and majority of noncoding RNAs whose functions are unknown and the overwhelming numbers of new regulatory connections generated from large-scale studies. Our discipline is the cornerstone of what’s needed to discover the functions of new molecules and mechanisms underlying their connectios.”