“We are one knot in a great web of being, building out of the vast past and (with luck) continuing billions of years into the future, until the sun dies, the last of its energy reaches Earth, and our local light goes out. The most appropriate response to the world is to realize, with awe, the ferocious mystery of being alive in it. And act accordingly. The worst thing anyone should be able to say about their life is also the greatest thing anyone can say: 'I tried my best.”