Liz Parrish

“Aging is one of the most visual diseases on the planet and includes things that we all know like wrinkles and grey hair, but also brain atrophy, muscle wasting and organ damage.”

“We do not collaborate with SENS at this time but we support their mission.”

“We can not control the aging reversal to a specific year today, that will come in the future. It is hypothesized that you will not reverse in physical appearance to less than a young adult. We see this in mice as well.”

“We are using both visual biomarkers, MRI and a panel of blood and tissue testing including work on telomere length with Spectracell and Life Length and epigenetic testing.”

“You have little to no response to AAV the first time your body sees it. If you used the same vector twice you would want to bump up immunosuppression. I believe there will be many new ways to deliver genes in the future as well.”

“Our science and advisory board think that nuclear lamin dysfunction is a side-effect of DNA damage and mutations, rather than the cause. We are currently trying to mend nuclear dysfunction using Human Telomerase reverse transcriptase.”

“I was awake for the therapy, it was documented by a film crew. I am proud to have taken part of helping millions of people even if it has bad results.”

“Epigenetics is very important. We are keeping a close eye on iPS cells and other genetic methods of reprogramming the epigenome.”

“I have aging as a disease.”

“We have a battery of tests planned at regular intervals including DNA methylation analysis, gene expression profile changes, telomere length (both TAT and QTRAP measured) and various other metrics that will highlight positive changes to aging biomarkers.”

“We are looking at gene therapies to Reverse Atherosclerosis, Regenerate muscles and tissue, Improve cell signaling, Clear misfolded Proteins, Rejuvenate the immune System, Clear Senescent Cells, and Treat Monogenic Diseases.”

“The biotech game is quickly changing. The people must demand their use of these treatments.”

“Crisper is great. The future of gene therapy looks bright.”

“I agree Maria Blasco has achieved amazing things with telomerase induction and we are hopeful this will translate to the human model.”