Charles Scott Sherrington

“Further study of central nervous action, however, finds central inhibition too extensive and ubiquitous to make it likely that it is confined solely to the taxis of antagonistic muscles.”

“That a strong stimulus to such an afferent nerve, exciting most or all of its fibres, should in regard to a given muscle develop inhibition and excitation concurrently is not surprising.”

“In some units it may suppress the motor discharge altogether, in some it may merely slow the motor discharge thus lessening the wave frequency of the contraction and so the tension.”

“Existence of an excited state is not a prerequisite for the production of inhibition; inhibition can exist apart from excitation no less than, when called forth against an excitation already in progress, it can suppress or moderate it.”